Anxa5 - annexin A5

Enables several functions, including P-type calcium transporter activity; calcium-dependent phospholipid binding activity; and receptor tyrosine kinase binding activity. Involved in several processes, including cellular response to gonadotropin-releasing hormone; cellular response to lead ion; and negative regulation of prolactin secretion. Located in several cellular components, including Z disc; intercalated disc; and perikaryon. Biomarker of several diseases, including Wilson disease; cryptorchidism; glomerulonephritis; hyperthyroidism; and myocardial infarction. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Orthologous to human ANXA5 (annexin A5). [provided by Alliance of Genome Resources, Apr 2022]