Smad1 - SMAD family member 1

Predicted to enable several functions, including SMAD binding activity; enzyme binding activity; and nucleic acid binding activity. Involved in several processes, including BMP signaling pathway; negative regulation of muscle cell apoptotic process; and positive regulation of dendrite morphogenesis. Located in cytoplasm and nucleus. Used to study pulmonary hypertension. Biomarker of glomerulonephritis; male infertility; nephrotic syndrome; and pulmonary hypertension. Orthologous to human SMAD1 (SMAD family member 1). [provided by Alliance of Genome Resources, Apr 2022]