Enables several functions, including carbohydrate binding activity; enzyme binding activity; and enzyme inhibitor activity. Involved in negative regulation of glucokinase activity; protein import into nucleus; and response to fructose. Located in cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (glucokinase regulator). [provided by Alliance of Genome Resources, Apr 2022]