Adrb3 - adrenoceptor beta 3

Enables epinephrine binding activity and norepinephrine binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; eating behavior; and response to cold. Located in nucleus. Biomarker of colitis; congestive heart failure; and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; obesity; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3). [provided by Alliance of Genome Resources, Apr 2022]