Cyp3a23-3a1 - cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in several processes, including oxidative demethylation; response to cadmium ion; and response to dexamethasone. Located in endoplasmic reticulum membrane. Biomarker of cholestasis and mental depression. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]