G6pc1 - glucose-6-phosphatase catalytic subunit 1

Enables glucose-6-phosphatase activity. Involved in several processes, including gluconeogenesis; phosphorylated carbohydrate dephosphorylation; and response to resveratrol. Located in intracellular membrane-bounded organelle. Used to study type 2 diabetes mellitus. Biomarker of fatty liver disease. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human G6PC1 (glucose-6-phosphatase catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]