Enables deoxyribonuclease I activity. Predicted to be involved in several processes, including DNA catabolic process, endonucleolytic; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Predicted to be located in cytoplasmic vesicle; extracellular region; and nuclear envelope. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human DNASE1 (deoxyribonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]