Cryba1 - crystallin, beta A1

Predicted to enable identical protein binding activity. Predicted to be a structural constituent of eye lens. Involved in several processes, including lens development in camera-type eye; negative regulation of intracellular signal transduction; and positive regulation of anoikis. Located in lysosome and nucleus. Used to study cataract; microphthalmia; and retinal detachment. Biomarker of ocular hypertension. Human ortholog(s) of this gene implicated in cataract and cataract 10 multiple types. Orthologous to human CRYBA1 (crystallin beta A1). [provided by Alliance of Genome Resources, Apr 2022]