Map3k12 - mitogen activated protein kinase kinase kinase 12

Predicted to enable JUN kinase kinase kinase activity; protein homodimerization activity; and protein kinase binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and protein phosphorylation. Predicted to act upstream of or within negative regulation of motor neuron apoptotic process. Predicted to be located in cytosol; growth cone; and plasma membrane. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12). [provided by Alliance of Genome Resources, Apr 2022]