Rock2 - Rho-associated coiled-coil containing protein kinase 2
Alias:
ROK
ROCK-II
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Sequence Homology
Transcripts & Proteins
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Predicted to enable Rho-dependent protein serine/threonine kinase activity. Involved in several processes, including positive regulation of cardiac muscle hypertrophy; positive regulation of connective tissue replacement; and positive regulation of cytokine production. Acts upstream of or within Rho protein signal transduction. Predicted to be located in cytoplasmic ribonucleoprotein granule; cytosol; and spindle pole centrosome. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; centrosome; and glutamatergic synapse. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2). [provided by Alliance of Genome Resources, Apr 2022]