Prkcz - protein kinase C, zeta

Enables several functions, including 14-3-3 protein binding activity; enzyme binding activity; and protein kinase C activity. Involved in several processes, including activation of phospholipase D activity; activation of protein kinase B activity; and positive regulation of cell communication. Located in several cellular components, including membrane raft; perinuclear region of cytoplasm; and stress fiber. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density. Used to study hyperglycemia. Biomarker of type 2 diabetes mellitus. Orthologous to human PRKCZ (protein kinase C zeta). [provided by Alliance of Genome Resources, Apr 2022]