Ppia - peptidylprolyl isomerase A

Enables cyclosporin A binding activity. Involved in negative regulation of phosphoprotein phosphatase activity. Predicted to be located in cytosol; extracellular region; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Used to study epilepsy. Human ortholog(s) of this gene implicated in cholangiocarcinoma and human immunodeficiency virus infectious disease. Orthologous to human PPIA (peptidylprolyl isomerase A). [provided by Alliance of Genome Resources, Apr 2022]