Plk1 - polo-like kinase 1

Predicted to enable several functions, including ATP binding activity; anaphase-promoting complex binding activity; and magnesium ion binding activity. Involved in polar body extrusion after meiotic divisions and response to antibiotic. Acts upstream of or within protein phosphorylation. Located in cytoplasm; nucleus; and spindle. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human PLK1 (polo like kinase 1). [provided by Alliance of Genome Resources, Apr 2022]