Kcna2 - potassium voltage-gated channel subfamily A member 2
Alias:
BK2
NGK1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
References Literature
Enables delayed rectifier potassium channel activity; kinesin binding activity; and outward rectifier potassium channel activity. Involved in neuronal action potential; potassium ion export across plasma membrane; and sensory perception of pain. Located in juxtaparanode region of axon and lamellipodium. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Is active in calyx of Held. Is integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 32. Orthologous to human KCNA2 (potassium voltage-gated channel subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]