Gabrb1 - gamma-aminobutyric acid type A receptor subunit beta1

Enables GABA receptor binding activity; GABA-A receptor activity; and ion channel activity. Involved in several processes, including cellular response to histamine; central nervous system neuron development; and response to progesterone. Located in several cellular components, including cytoplasm; dendrite; and nuclear envelope. Is integral component of plasma membrane. Part of GABA-A receptor complex. Is active in GABA-ergic synapse. Biomarker of hepatic encephalopathy. Human ortholog(s) of this gene implicated in autistic disorder and developmental and epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor subunit beta1). [provided by Alliance of Genome Resources, Apr 2022]