Cd44 - CD44 molecule (Indian blood group)

Enables epidermal growth factor receptor binding activity; phosphoprotein binding activity; and protein kinase binding activity. Involved in several processes, including blood vessel maturation; macrophage fusion; and positive regulation of neutrophil apoptotic process. Located in apical plasma membrane; basolateral plasma membrane; and nucleus. Part of protein-containing complex. Biomarker of borna disease and cholestasis. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)). [provided by Alliance of Genome Resources, Apr 2022]