Apobec1 - apolipoprotein B mRNA editing enzyme catalytic subunit 1

Enables several functions, including enzyme activator activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; and ribonucleoprotein complex binding activity. Involved in several processes, including cellular response to insulin stimulus; nucleic acid metabolic process; and positive regulation of mRNA modification. Located in cytoplasm and nucleus. Used to study familial hyperlipidemia and liver benign neoplasm. Biomarker of colon cancer and obesity. Orthologous to human APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]