Grk3 - G protein-coupled receptor kinase 3

Enables D1 dopamine receptor binding activity; G protein-coupled receptor kinase activity; and beta-adrenergic receptor kinase activity. Involved in several processes, including cellular protein metabolic process; desensitization of G protein-coupled receptor signaling pathway; and response to morphine. Located in several cellular components, including Z disc; dendrite; and sperm midpiece. Biomarker of Parkinson's disease; hypertension; and hypothyroidism. Orthologous to human GRK3 (G protein-coupled receptor kinase 3). [provided by Alliance of Genome Resources, Apr 2022]