Mgp - matrix Gla protein

Enables calcium ion binding activity and calcium-dependent protein binding activity. Involved in several processes, including branching morphogenesis of an epithelial tube; response to calcium ion; and response to glucocorticoid. Located in collagen-containing extracellular matrix; endoplasmic reticulum; and extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in arteriosclerosis; calcinosis; and myocardial infarction. Orthologous to human MGP (matrix Gla protein). [provided by Alliance of Genome Resources, Apr 2022]