Enables carboxylic ester hydrolase activity. Involved in female pregnancy; response to xenobiotic stimulus; and triglyceride catabolic process. Located in cytoplasm and extracellular space. Used to study arteriosclerosis and heart disease. Biomarker of obesity. Human ortholog(s) of this gene implicated in familial partial lipodystrophy type 6 and hypertension. Orthologous to human LIPE (lipase E, hormone sensitive type). [provided by Alliance of Genome Resources, Apr 2022]