Ms4a2 - membrane spanning 4-domains A2

Enables SH2 domain binding activity; phosphoprotein binding activity; and protein kinase binding activity. Contributes to IgE receptor activity. Involved in several processes, including activation of phospholipase C activity; positive regulation of mast cell degranulation; and protein kinase C-activating G protein-coupled receptor signaling pathway. Located in endosome and membrane raft. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; and rhinitis. Orthologous to human MS4A2 (membrane spanning 4-domains A2). [provided by Alliance of Genome Resources, Apr 2022]