Dgat2 - diacylglycerol O-acyltransferase 2

Enables diacylglycerol O-acyltransferase activity. Involved in several processes, including bile acid signaling pathway; positive regulation of gluconeogenesis; and regulation of lipid metabolic process. Located in intracellular membrane-bounded organelle. Used to study fatty liver disease. Biomarker of chronic kidney disease; non-alcoholic fatty liver disease; and premature menopause. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]