Sfpq - splicing factor proline and glutamine rich

Predicted to enable several functions, including chromatin binding activity; histone deacetylase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including alternative mRNA splicing, via spliceosome; dendritic transport of messenger ribonucleoprotein complex; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromosome organization; double-strand break repair via homologous recombination; and positive regulation of sister chromatid cohesion. Predicted to be located in chromatin; nuclear matrix; and paraspeckles. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SFPQ (splicing factor proline and glutamine rich). [provided by Alliance of Genome Resources, Apr 2022]