Rxra - retinoid X receptor alpha

Enables protein domain specific binding activity and retinoic acid receptor binding activity. Contributes to double-stranded DNA binding activity. Involved in several processes, including cellular response to insulin stimulus; response to retinoic acid; and response to vitamin. Located in axon and nucleus. Biomarker of alcoholic cardiomyopathy and prostate carcinoma in situ. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]