Proc - protein C, inactivator of coagulation factors Va and VIIIa

Enables oligopeptidase activity and protein self-association. Involved in liver development; negative regulation of blood coagulation; and proteolysis. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including antiphospholipid syndrome; artery disease (multiple); placental abruption; thrombophilia (multiple); and toxic shock syndrome. Orthologous to human PROC (protein C, inactivator of coagulation factors Va and VIIIa). [provided by Alliance of Genome Resources, Apr 2022]