Pdgfa - platelet derived growth factor subunit A

Predicted to enable several functions, including platelet-derived growth factor binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in several processes, including male gonad development; response to estradiol; and response to retinoic acid. Predicted to be located in cell surface and microvillus. Predicted to be active in extracellular space. Biomarker of chronic ulcer of skin; oligohydramnios; pancreatitis; pulmonary hypertension; and renovascular hypertension. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human PDGFA (platelet derived growth factor subunit A). [provided by Alliance of Genome Resources, Apr 2022]