Dspp - dentin sialophosphoprotein

Enables collagen binding activity. Involved in several processes, including animal organ development; cellular response to dexamethasone stimulus; and odontoblast differentiation. Acts upstream of or within positive regulation of calcium ion import. Located in several cellular components, including collagen-containing extracellular matrix; nucleus; and plasma membrane. Biomarker of osteoporosis. Human ortholog(s) of this gene implicated in dentinogenesis imperfecta. Orthologous to human DSPP (dentin sialophosphoprotein). [provided by Alliance of Genome Resources, Apr 2022]