Bgn - biglycan

Predicted to enable extracellular matrix binding activity and glycosaminoglycan binding activity. Involved in blood vessel remodeling. Predicted to be located in several cellular components, including cell surface; sarcolemma; and transport vesicle. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Meester-Loeys syndrome and X-linked spondyloepimetaphyseal dysplasia. Orthologous to human BGN (biglycan). [provided by Alliance of Genome Resources, Apr 2022]