Cyp17a1 - cytochrome P450, family 17, subfamily a, polypeptide 1

Enables steroid 17-alpha-monooxygenase activity. Involved in several processes, including animal organ development; response to fungicide; and response to herbicide. Located in cell projection; endoplasmic reticulum; and neuronal cell body. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including cholelithiasis; congenital adrenal hyperplasia; gallbladder cancer; osteoporosis; and prostate cancer. Orthologous to human CYP17A1 (cytochrome P450 family 17 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]