Avpr2 - arginine vasopressin receptor 2

Predicted to enable peptide binding activity and vasopressin receptor activity. Involved in several processes, including negative regulation of renal sodium excretion; negative regulation of urine volume; and positive regulation of systemic arterial blood pressure. Predicted to be located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Predicted to be integral component of plasma membrane. Used to study hypertension. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis. Orthologous to human AVPR2 (arginine vasopressin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]