Chrna5 - cholinergic receptor nicotinic alpha 5 subunit

Enables acetylcholine binding activity and acetylcholine-gated cation-selective channel activity. Predicted to be involved in several processes, including behavioral response to nicotine; cholinergic synaptic transmission; and regulation of synaptic vesicle exocytosis. Located in dendrite; neuronal cell body; and plasma membrane. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit). [provided by Alliance of Genome Resources, Apr 2022]