Enables ATP binding activity; glucose binding activity; and hexokinase activity. Involved in several processes, including carbohydrate phosphorylation; lactation; and response to ischemia. Located in several cellular components, including cytosol; mitochondrion; and sarcoplasmic reticulum. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (hexokinase 2). [provided by Alliance of Genome Resources, Apr 2022]