P2rx6 - purinergic receptor P2X 6

Enables extracellularly ATP-gated cation channel activity. Predicted to be involved in cation transmembrane transport; cell surface receptor signaling pathway; and response to ATP. Located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Is active in glutamatergic synapse and parallel fiber to Purkinje cell synapse. Is integral component of postsynaptic specialization membrane. Orthologous to human P2RX6 (purinergic receptor P2X 6). [provided by Alliance of Genome Resources, Apr 2022]