Gip - gastric inhibitory polypeptide

Enables signaling receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of glucose transmembrane transport; and triglyceride homeostasis. Located in cytoplasm; extracellular space; and neuronal cell body. Used to study type 2 diabetes mellitus. Biomarker of hyperinsulinism; hypothyroidism; obesity; and pancreas disease. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human GIP (gastric inhibitory polypeptide). [provided by Alliance of Genome Resources, Apr 2022]