Calcrl - calcitonin receptor like receptor

Predicted to enable adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in negative regulation of inflammatory response and negative regulation of smooth muscle contraction. Predicted to be located in endoplasmic reticulum; endosome; and lysosome. Predicted to be part of CGRP receptor complex and adrenomedullin receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CALCRL (calcitonin receptor like receptor). [provided by Alliance of Genome Resources, Apr 2022]