Fgfr2 - fibroblast growth factor receptor 2

Enables fibroblast growth factor binding activity and fibroblast growth factor-activated receptor activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to retinoic acid; and positive regulation of smooth muscle cell proliferation. Located in cell surface; cytoplasm; and nucleus. Used to study prostate cancer and retinitis pigmentosa. Biomarker of hypospadias. Human ortholog(s) of this gene implicated in several diseases, including Beare-Stevenson cutis gyrata syndrome; Jackson-Weiss syndrome; LADD syndrome; dysgerminoma; and synostosis (multiple). Orthologous to human FGFR2 (fibroblast growth factor receptor 2). [provided by Alliance of Genome Resources, Apr 2022]