Enables several functions, including cation transmembrane transporter activity; identical protein binding activity; and toxin transmembrane transporter activity. Involved in several processes, including catecholamine transport; ion transmembrane transport; and toxin transport. Located in apical plasma membrane and basolateral plasma membrane. Is integral component of plasma membrane. Used to study acute kidney failure. Biomarker of asthma; extrahepatic cholestasis; and intrahepatic cholestasis. Orthologous to human SLC22A1 (solute carrier family 22 member 1). [provided by Alliance of Genome Resources, Apr 2022]