Tgfa - transforming growth factor alpha

Enables epidermal growth factor receptor binding activity. Involved in several processes, including hepatocyte proliferation; negative regulation of apoptotic process; and wound healing. Located in extracellular space and nucleus. Colocalizes with plasma membrane. Used to study pancreatic cancer. Biomarker of acute kidney failure and hepatocellular carcinoma. Human ortholog(s) of this gene implicated in gastroenteritis. Orthologous to human TGFA (transforming growth factor alpha). [provided by Alliance of Genome Resources, Apr 2022]