Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to organic cyclic compound; and response to vitamin B6. Located in extracellular space. Used to study adult respiratory distress syndrome. Biomarker of uveitis. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3). [provided by Alliance of Genome Resources, Apr 2022]