Serpina3c - serine (or cysteine) proteinase inhibitor, clade A, member 3C

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; and positive regulation of apoptotic process. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3). [provided by Alliance of Genome Resources, Apr 2022]