Scnn1g - sodium channel epithelial 1 subunit gamma

Enables WW domain binding activity and ligand-gated sodium channel activity. Contributes to sodium ion transmembrane transporter activity. Involved in response to hypoxia; sodium ion transport; and wound healing, spreading of epidermal cells. Located in apical plasma membrane and cell surface. Human ortholog(s) of this gene implicated in Liddle syndrome; autosomal recessive pseudohypoaldosteronism type 1; bronchiectasis 3; and pseudohypoaldosteronism. Orthologous to human SCNN1G (sodium channel epithelial 1 subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]