Pomc - proopiomelanocortin

Predicted to enable hormone activity and melanocortin receptor binding activity. Predicted to be involved in several processes, including cortisol secretion; positive regulation of cAMP-mediated signaling; and regulation of gene expression. Predicted to act upstream of or within several processes, including calcium-mediated signaling; glucose homeostasis; and regulation of glycogen metabolic process. Located in extracellular region. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Orthologous to human POMC (proopiomelanocortin). [provided by Alliance of Genome Resources, Apr 2022]