Enables phenylethanolamine N-methyltransferase activity. Involved in several processes, including catecholamine metabolic process; cellular response to dexamethasone stimulus; and response to peptide hormone. Located in several cellular components, including axon; dendrite; and perikaryon. Biomarker of hypertension and hypoglycemia. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]