Predicted to enable keratin filament binding activity. Predicted to be a structural constituent of skin epidermis. Involved in epidermal cell differentiation. Predicted to be located in cornified envelope; cytoplasmic ribonucleoprotein granule; and keratohyalin granule. Human ortholog(s) of this gene implicated in atopic dermatitis 2 and ichthyosis vulgaris. Orthologous to human FLG (filaggrin). [provided by Alliance of Genome Resources, Apr 2022]