Enables beta-2 adrenergic receptor binding activity; cyclic-nucleotide phosphodiesterase activity; and enzyme binding activity. Involved in several processes, including positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; and regulation of signal transduction. Located in several cellular components, including Golgi apparatus; centrosome; and myofibril. Part of protein-containing complex. Used to study mental depression. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in acrodysostosis. Orthologous to human PDE4D (phosphodiesterase 4D). [provided by Alliance of Genome Resources, Apr 2022]