Oas1b - 2-5 oligoadenylate synthetase 1B

Predicted to enable 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Predicted to be involved in defense response to virus; negative regulation of viral genome replication; and regulation of ribonuclease activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol; membrane; and nucleoplasm. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]