Ngef - neuronal guanine nucleotide exchange factor

Predicted to enable ephrin receptor binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity; ephrin receptor signaling pathway; and negative regulation of dendritic spine morphogenesis. Predicted to be located in cytoplasm; growth cone; and membrane. Predicted to be active in glutamatergic synapse. Orthologous to human NGEF (neuronal guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]