Tpcn1 - two pore segment channel 1

Predicted to enable several functions, including cation channel activity; phosphatidylinositol-3,5-bisphosphate binding activity; and protein homodimerization activity. Predicted to be involved in endocytosis involved in viral entry into host cell; positive regulation of autophagy; and sodium ion transmembrane transport. Predicted to be located in early endosome membrane; endolysosome; and recycling endosome membrane. Predicted to be integral component of membrane. Predicted to be active in endosome membrane and lysosomal membrane. Orthologous to human TPCN1 (two pore segment channel 1). [provided by Alliance of Genome Resources, Apr 2022]