Kcne2 - potassium voltage-gated channel, Isk-related subfamily, gene 2

Predicted to enable several functions, including identical protein binding activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to contribute to delayed rectifier potassium channel activity; inward rectifier potassium channel activity; and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Involved in iodide transport; multicellular organismal response to stress; and myo-inositol transport. Acts upstream of or within several processes, including potassium ion transmembrane transport; regulation of ventricular cardiac muscle cell membrane repolarization; and ventricular cardiac muscle cell action potential. Located in membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in atrial fibrillation; familial atrial fibrillation; long QT syndrome; and long QT syndrome 6. Orthologous to human KCNE2 (potassium voltage-gated channel subfamily E regulatory subunit 2). [provided by Alliance of Genome Resources, Apr 2022]