Muc2 - mucin 2, oligomeric mucus/gel-forming

Enables identical protein binding activity. Involved in several processes, including cellular response to tumor necrosis factor; response to lipopolysaccharide; and response to vitamin A. Located in cytoplasm; mucus layer; and nucleus. Used to study colitis; intestinal disease; and pneumonia. Biomarker of several diseases, including colitis (multiple); colon cancer; liver cirrhosis; mucositis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in asthma. Orthologous to human MUC2 (mucin 2, oligomeric mucus/gel-forming). [provided by Alliance of Genome Resources, Apr 2022]